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In PD patients there are reports of decreased CSF post-proline cleaving enzyme (Hagihara and Nagatsu, 1987), increased dipeptidyl-aminopeptidase II (Hagihara et al., 1987), normal dipeptidyl-aminopeptidase IV (Hagihara et al., 1987), and normal glutamic oxaloacetic transaminase (GOT) (Steen and Thomas, 1962

When applied to the scalp or used systemically, they influence key processes that affect hair health

Moreover, conjugation strategies incorporating fatty acids or polysarcosine help reduce renal clearance, evade anti-PEG immune responses, and shield immunogenic epitopes without compromising GLP-1R targeting efficiency

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