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Injection forms of these drugs need to be refrigerated, while oral tablet forms of these drugs can be stored at room temperature

Both use a gradual dose escalation to minimize GI side effects, sharing the same schedule through 1.0 mg before diverging

While facing these lawsuits, Eli Lilly and Novo Nordisk have initiated legal actions against compounding pharmacies, seen by some as efforts to deflect accountability for the adverse effects, blaming the compounding manufacturers for creating sub-par medications that have caused the side effects

Initial randomized clinical trials indicate possible reductions in craving and substance intake, though findings are mixed and ongoing studies are needed to determine safety and efficacy in patients with alcohol and other substance use disorders

Activation of -adrenoceptors in the bed nucleus of the stria terminalis induces food intake reduction and anxiety-like behaviors