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The in-vivo part of the study lasted 11 days

Sex difference in susceptibility to acetaminophen hepatotoxicity is reversed by buthionine sulfoximine

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Discussion This study shows that administration of metformin 30 and 60 min before an intraduodenal glucose load is more effective than its administration at the start of the glucose infusion in terms of both reducing glycaemia and augmenting GLP-1 release in participants with metformin-treated type 2 diabetes