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Why Medical Guidelines Discourage Phentermine and Wegovy Combination No large clinical trials have studied the safety of phentermine plus Wegovy together in humans

Epidemiological data underscore the widespread use of GLP-1 medications, with approximately 12% of adults in the United States (around 31 million people) having used GLP-1 drugs, 6% of whom are currently using them primarily for managing diabetes (Montero et al

This is particularly important during a weight loss phase, where dietary changes are common, and maintaining nutrient status is key

There is no absolute contraindication to taking Wegovy and Wellbutrin together, though it should be noted that concurrent use represents an off-label prescribing decision that should follow careful clinical assessment and shared decision-making

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