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Sleep 37 , 17571765 (2014)

Trials typically incorporate biomarker endpoints such as ER/ER ratios, aromatase activity, plasma isoflavone or polyphenol concentrations, immune cell phenotyping, cytokine panels, oxidative stress markers and microbiome profile which are used to provide mechanistic read-outs of supplement activity and to inform patient stratification approaches (231)

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The benefit of GLP-1 medications is that they dont require daily doses or even coming back into our office