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Healthcare providers closely monitor for side effects, particularly gastrointestinal issues and dehydration

Hyper- kalemia-related discontinuation of renin-angiotensin-aldosterone system inhibitors and clinical outcomes in CKD: A population-based cohort study

In toxin-induced PD mouse models, DA-JC1, a novel dual GLP-1/GIP receptor agonist, improved motor impairment, increased the number of dopaminergic neurons in the substantia nigra, enhanced BDNF levels, and modulated apoptosis signaling pathways by altering the expression of Bax and Bcl-2 [89, 90]

These combined effects may explain why retatrutide has produced significant weight loss in clinical trials

Sugio, S., Kashima, A., Mochizuki, S., Noda, M