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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging Baar MP, Brandt RMC, Putavet DA, et al
Example: Diclofenac SR, Metoprolol SR Controlled Release (CR) The release rate is precisely controlled to maintain a nearly constant plasma concentration (1224 hours)
Adair-Kirk TL, Atkinson JJ, Griffin GL, Watson MA, Kelley DG, DeMello D, Senior RM, Betsuyaku T: Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells
How genetically engineered mouse tumor models provide insights into human cancers
The shorter length means less tissue penetration but may not reach deep enough for people with thick subcutaneous layers
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