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Second, there was substantial heterogeneity across outcomes (I 2 values exceeding 90% in several analyses)

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In 4-week clinical studies, the average ADHD-RS score was reduced by: 18.3 to 26.7 in children ages 6 to 17 who took Vyvanse, depending on their dose 16.2 to 18.6 in adults who took Vyvanse, depending on their dose 6.2 to 12.8 in children ages 6 to 17 who took a placebo 8.2 in adults who took a placebo Vyvanse was also effective in longer studies in adults and children