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State Medicaid programs have the authority to determine whether they will cover weight-loss drugs

These symptoms require immediate emergency medical care

In the pivotal SURPASS-2 trial, which compared tirzepatide directly with semaglutide (another GLP-1 receptor agonist), no significant difference in thrombotic event rates was observed between treatment groups, though event numbers were low

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The company will try to extend exclusivity where possible through delivery mechanism patents or other lifecycle management strategies but the clock is ticking