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Peer review Peer review information Nature Metabolism thanks Timo Mller and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Among the leading non-genetic etiologies causally linked to male infertility is oxidative stress, a pathology that arises as a consequence of elevated levels of reactive oxygen species (ROS) within the male germline (74)

Pinealon: the neuroprotective sleep optimizer Pinealon is a tripeptide consisting of three amino acids: glutamic acid, aspartic acid, and arginine (Glu-Asp-Arg)

Boulardii, a gut-friendly, acid-resistant yeast that helps support the newly added microorganisms

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