Its role is in the formation of normal red blood cells in the bone marrow
That is why tirzepatide became such a standout
So what happens is certain artificial sweeteners in particular saccharin disrupt the microbiome and make the environment within the gut, that mucosal lining more favorable to, to bacteria microbiota that are not good for the organism
NR : Not reported Design In the obesity trial, 338 participants (mean age 48 years, 48% women, mean BMI 37.3 kg/m 2 ) were randomised (2:1:1:1:1:2:2) to retatrutide 1 mg, 4 mg (titration), 4 mg (no titration), 8 mg (slow titration), 8 mg (fast titration), 12 mg or placebo over 48 weeks [45]
From the MAC line I would say, and I still use them today, that I love the MAC Lip Spice Pencil