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Roldan EJ, Perez Lloret A

Benfotiamine is a synthetic, fat-soluble form of thiamine

543 Additionally, patient education on proper foot care, including daily inspections, appropriate footwear, and maintaining foot hygiene, is crucial in preventing severe foot-related complications

Supplementing with a comprehensive prenatal or postnatal vitamin that includes B12

The study confirmed FOXO4-DRI was effective across senescent cells generated by different methods (irradiation, doxorubicin, and replication stress), and documented that pre-treatment with FOXO4-DRI attenuated the dedifferentiation of chondrocytes during in vitro expansion establishing it as a valuable tool for research into senescent cell biology in cartilage and musculoskeletal models