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A review published in 2024 by Sikiric and colleagues found that this peptide is highly stable in gastric environments (the acidity inside a living stomach) and summarized its broad range of investigated biological activities

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Moreover, these results of the multi-lineage differentiation capacity were validated by the upregulation of the FABP4 known as intracellular lipid chaperones, which regulate lipid trafficking and responses in cells [39,40], as well as PPAR critically involved in the regulation of a large number of genes, which regulate energy homeostasis, glucose triglyceride and lipoprotein metabolism, de novo lipogenesis, fatty acid uptake, oxidation, storage and export, cell proliferation, inflammation, and vascular tissue function [41]