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2009 Marta Anna Lech, Monika Lekiewicz, Kinga Kamiska, Zofia Rog, Elbieta Lorenc-Koci

Uric acid itself is a chemical byproduct created when the body processes substances called purines , which are found naturally in the body as well as some foods and drinks including some fish and shellfish, dried beans and peas, and alcohol

The observed potentiation of both the cAMP and Arr signaling pathways was consistent with our hypothesis that BETP treatment resulted in general receptor sensitization, rather than a pathway-specific signaling amplification

After four weeks, the dose typically increases to 0.5mg per week for another four weeks, then continues titrating upward