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As we get older, mitochondria accrue more and more mutations, release more and more inflammation provoking debris (Munoz-Pinto et al., 2021), countermeasures to mitigate the harm begin to fail (Lane, 2015), and keeping the microbiota healthy becomes less and less feasible

While IGF-1 supports collagen production, long-term synthetic exposure can increase cancer risk , making it unsuitable for cosmetic or anti-aging use

Elucidating the role of site-specific nitration of -synuclein in the pathogenesis of Parkinson's disease via protein semisynthesis and mutagenesis

demonstrated that activation of TRPV1 by dietary capsaicin could mitigate the adverse effects of a high-salt diet on oxidative phosphorylation efficiency at Complex I (OXPHOS)[187]

doi: 10.1016/j.peptides.2019.170230 48 DeaconCFPlamboeckARosenkildeMMde HeerJHolstJJ