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94,101 In a randomized, double-blind, placebo controlled trial conducted at 191 clinical sites in 27 countries comparing the effects of liraglutide (3 mg daily) vs placebo in people with prediabetes and obesity, the time to onset of diabetes over 160 weeks among all randomized individuals was 2.7 times longer with liraglutide (n = 1505) than with placebo (n = 749), corresponding with an HR of 2.1

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