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The speed of results varies among individuals

Biosens Bioelectron 56:180185 Rao H, Lu Z, Gel H, Liu X, Chen B et al (2017) Electrochemical creatinine sensor based on a glassy carbon electrode modified with a molecularly imprinted polymer and Ni@polyaniline nanocomposite

The suggestion that progressive emphysematous destruction is associated with down-regulation of genes involved in or downstream of tissue remodeling and wound repair pathways supports a role for defects in ECM homeostasis and angiogenesis in the emphysematous destruction that occurs with chronic inflammation in COPD

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I think medication is effective and worth trying