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Pfizer provides update on oral GLP-1 receptor agonist danuglipron

Serious but rare adverse effects include pancreatitis, hypoglycaemia when combined with insulin or sulfonylureas, and gallbladder problems

They might even be convinced that these supplements are the better option: Supergut, according to its marketing, is non-pharmaceutical, affordable, convenient, and comes with none of the unpleasant side effects of the obesity drugs, offering a sustainable approach to achieve lasting results. Other brands use phrases such as hunger quieting and curbs cravings, borrowed directly from the Ozempic playbook

These drugs work by reducing cravings or causing severe nausea when alcohol is consumed, but they are seldom prescribed for a variety of reasons

In an animal model of depression and diabetes, however, exendin-4 led to antidepressant-like effects, which was associated with changes in microglial function 168