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Serious side effects, including potential kidney failure and pancreatitis, are associated with tirzepatide use, necessitating careful monitoring

Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism

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Beyond direct mitochondrial support, KD also protects dopaminergic neurons in rat models of PD by upregulating glutathione, highlighting an additional protective mechanism [61]