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The price of the vial starts at $349 per month for the 2.5-mg dose, and $499 for all other doses (5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg)

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The molecular responses observed vary with receptor subtype, concentration, exposure time, and experimental model, and PT141 is used to characterise melanocortinreceptor signalling rather than to infer defined biological or physiological outcomes

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Defects in regulatory T cells (Tregs) and increased expression of inflammasome components further amplify sensitivity to thyroid autoantigens