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The study demonstrated that in spontaneously hypertensive rats, liraglutide reduced circulating Ang II levels, upregulated cardiac angiotensin II type 2 receptor (AT2R) and angiotensin-converting enzyme-2 (ACE2) expression, and attenuated myocardial hypertrophy [145]

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This was the first year ICD-10-CM was implemented into the HIPAA code set.