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Keywords: sex differences, GLP-1, exendin-4, semaglutide, estrogens, obesity Despite ample evidence for sex differences in the action of key metabolic hormones and established actions of gonadal steroids on ingestive and motivated behaviors, preclinical studies still do not consistently test female subjects, and when they do, they often fail to show sex-disaggregated data

doi: 10.1242/jcs.02561

It requires longitudinal tracking, basket-level analysis, and behavioral segmentation models that capture habit rewiring in real time

thus, sexes were combined for those experiments