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10.1089/ham.2017.0126 114 WangC.XuM.WuQ.LiuX.LiuZ.XuS

Taking metformin can cause side effects such as stomach pain, heartburn, gas, bloating, upset stomach, diarrhea, constipation, metallic taste, and headache

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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure