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It targets amylin receptor biology , which is built from the calcitonin receptor paired with RAMP proteins to form distinct receptor complexes (often described as AMY receptor subtypes)

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Studies in mice have shown that GLP-1s also reduce "nicotine-induced increases in dopamine release" in a specific brain area, "a common mechanism underlying the rewarding effects of addictive drugs," the researchers explained

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Burrin DG, Stoll B, Guan X, Cui L, Chang X, Hadsell D