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do not inject directly onto the lyophilized cake and do not shake the vial, as mechanical agitation promotes aggregation in peptides

Further well-designed, multicenter randomized controlled trials employing standardized and sensitive apnea detection methods are essential to definitively evaluate this potential application (45, 78)

So what follows is a walk through what the in-vitro evidence honestly supports, what it doesnt, and the handful of places where careful researchers still shrug and admit theyre not sure

The most common ones include mild irritation at the injection site