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It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins ( A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing ( Additionally, participants experienced a significant increase in energy by day 14 ( Summary MSM may help reduce allergy-related symptoms including coughing, shortness of breath, congestion, sneezing and fatigue by reducing inflammation