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Prioritise protein to protect muscle Research suggests that people losing weight on GLP-1 receptor agonists often fall well short of recommended protein targets, which can accelerate muscle loss
"These medications can raise resting heart rate in some people, and this can make normal sensations more noticeable
Similarly, in LDL receptor knock-out mice subjected to a Western diet, treatment-reduced plaque lesions and semaglutide were reported to affect the expression of several genes related to cholesterol metabolism, leukocyte recruitment, adhesion and extravasation, and also extracellular matrix protein turnover [35]
Dixon W
Individual responses to the appetite-suppressing properties vary considerably, with some patients noticing that the initial dramatic reduction in hunger becomes less pronounced after several months of treatment, even when maintaining the maximum 2.4 mg weekly dose
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