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Based upon our study, GLP-1 analogues demonstrate superiority in clinical efficacy (0.41%) and weight loss (1.55 kg) but have a higher incidence of gastrointestinal events and require delivery by subcutaneous injection

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A study in July 2024 by researchers at Mass Eye and Ear in Boston found that people taking semaglutide for type 2 diabetes or weight loss had a higher risk of developing nonarteritic anterior ischemic optic neuropathy, an eye condition that can cause blindness, than people taking medications other than GLP-1 drugs for diabetes or obesity