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FOXO4-DRI was apparently linked to lower levels of senescence markers (p53, p21, p16) and lower levels of several Senescence-Associated Secretory Phenotype factors in such cell cultures, especially IL-1, IL-6, and TGF-

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Thymosin Alpha-1 may help address both of these challenges by supporting immune competence while promoting inflammatory balance

doi: 10.1016/s0024-3205(99)00314-8

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