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LAT1 ( SLC7A5 ) is the main BCAA transporter, which belongs to the Na + - and pH-independent L-type amino acid transporters (system L/antiporter) SLC7 family and is highly expressed in many cancers, including the most frequently diagnosed cancers, such as lung cancer, prostate cancer, and breast cancer (Kandasamy et al., 2018

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Yes polymorphisms in glutathione S-transferase genes (GSTM1-null and GSTT1-null) reduce Phase II detoxification capacity and are present in 4060% of some populations

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