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The first wave of NASH candidates includes: Obeticholic acid (Intercept Pharmaceuticals) Intercepts application for accelerated approval for obeticholic acid (OCA) was denied by the FDA on June 29, 2020, contrary to expectations

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By mimicking the action of GLP-1, it helps regulate insulin secretion and reduce glucagon release, leading to improved blood sugar control

Orders for oral semaglutide (Rybelsus) were excluded due to low frequency and its limited indication for weight loss

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