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Ethics declarations Conflict of interest All the authors agree with the content of the article and declare no conflict of interest (personal, academic or financial) associated with this study

A) mice administered Dihexa through a cannula, B) mice administered Dihexa via intraperitoneal injection, and C) mice administered Dihexa via oral delivery methods 2) In order to determine whether AngIV is involved in the development of Alzheimers, the research team of Sun et al detected the baseline levels of AngIV in both wild type and APP/PS1 mice

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Future research should focus on refining strategies that target estrogen pathways specifically in the skin, considering both genomic and non-genomic routes, to promote effective and safe wound healing interventions for older adults

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