Gentle stretching exercises, particularly before bedtime and before physical activity, can reduce the frequency and severity of muscle cramps
They can improve epithelial barrier function, regulate immune responses, and are commonly used to prevent obesity and treat intestinal dysbiosis (Li et al., 2020
It activates another set of receptors (GIP) along with GLP-1
According to the MHRA/EMC Summary of Product Characteristics, the most common adverse effects include: Nausea very common (affects more than 1 in 10 people), often most pronounced when starting treatment or increasing the dose Vomiting very common, typically improves as the body adjusts to the medication Diarrhoea very common Abdominal pain or discomfort common (affects up to 1 in 10 people) Decreased appetite common Constipation common Dyspepsia (indigestion) common, including bloating and flatulence These gastrointestinal effects are generally most prominent during the initial weeks of treatment and often diminish over time as the body adapts
However, a study in Obesity cited a lack of evidence for the effectiveness of other OTC supplements
