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By binding to these receptorsprimarily located in the pituitary gland and the hypothalamusit initiates a cascade of signals that mimic the action of the natural hormone ghrelin
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Healthcare regulators, including the UKs MHRA and NICE, have carefully reviewed the evidence and continue to endorse GLP-1 receptor agonists, provided patients and prescribers remain aware of the very small potential risk and take appropriate precautions
5A and Supporting Fig
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