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The molecular landscape of conventional melanomas in children mimics the UV-induced mutational spectrum found in melanomas in adults, including driver mutation in the RAS/RAF/mitogen-activated protein kinase pathway, alterations in the phosphatase and tensin homolog ( PTEN ) tumor suppressor gene and, notably, transcription- activating mutations of the telomerase reverse transcriptase ( TERT ) promoter ( TERT-p ) resulting in increased TERT expression [18]

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These could be signs of more serious complications that require medical attention

The agency has flagged it among bulk substances it sees as safety risks for compounding, and its status is shifting: a federal compounding advisory review is set for July 2026 to weigh whether licensed pharmacies can prepare it

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