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The SURMOUNT-1 trial for weight management showed similar patterns, with gastrointestinal events being the most common adverse reactions and a leading cause of treatment discontinuation

In a study comparing the effectiveness of the active ingredients in Mounjaro and Wegovy for weight loss, the average weight loss was greater in the tirzepatide (Mounjaro) group (15.3%) than the semaglutide (Wegovy) group (8.3%) after 12 months

However, if a patient reports unusual bruising, prolonged bleeding from minor cuts, or frequent nosebleeds while on both agents, a platelet count and bleeding time are reasonable next steps

We recommend that you find a local provider in your community that participates in your government payer program

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