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Deletion of IGF-1 receptors in cardiomyocytes attenuates cardiac aging in male mice

Tirzepatide's dual GLP-1 and GIP receptor activity produces slightly greater weight loss (up to 22% in SURMOUNT trials) and superior metabolic improvements in glucose control

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Hedonic eating in PraderWilli syndrome is associated with blunted PYY secretion

Here, we show that peroxynitrite added exogenously or generated endogenously in response to exposure to an NO donor or oxidized low-density lipoproteins (oxLDL) increases p21ras activity