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"Formulary Updates: GLP-1 Weight Management Medications." Wegovy moved to preferred status July 2025

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Others have reported an increase in anxiety

Participants receiving semaglutide 7.2 mg achieved 20.7% average weight reduction, with 33% of patients losing more than 25% of their body weight ^1

Mechano-responsive expression: IGF-1 gene splicing toward MGF is driven by mechanical strain in muscle-cell models, linking loading to the proposed repair signal [4]