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Iron deficiency can affect the synthesis of Fe-S clusters, heme, and other proteins, thereby interfering with normal cellular functions

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[71] Data from the United Kingdom Clinical Practice Research Datalink showed that in patients with HbA1c 7%, a years delay in receiving treatment intensification was associated with significantly increased risk of MI, HF, composite CV events, and stroke by 67%, 64%, 62%, and 51%, respectively [72]

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