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Small, dense HDL 3 particles attenuate apoptosis in endothelial cells: pivotal role of apolipoprotein A-I

This is consistent with what is happening in practice, but it carries serious risks

The Journal of Nutrition 137(7):1757-1762

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Single-pathway therapies may persist in specific niches where their particular advantages outweigh the benefits of increased complexity, but their role as first-line treatments appears increasingly challenged