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It was originally developed in Russia at the Institute of Molecular Genetics and has been studied in scientific literature for several decades

The clinical development program was discontinued due to insufficient weight loss efficacy rather than safety concerns

Coronary artery calcification and aortic valve calcification in patients with kidney failure: A sex-disaggregated study

As of August 2024, three doses of Wegovy remain in limited availability: 0.25 mg/0.5 mL 0.5 mg/0.5 mL 1 mg/0.5 mL The FDA database lists the estimated shortage duration for these doses as "TBD" (To Be Determined)

Core conclusions summary 1