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For this reason, patients who have had, or have family members who have ever had medullary thyroid carcinoma should not use liraglutide, nor should patients who have an endocrine system condition called multiple endocrine neoplasia syndrome type 2

One exception is in addiction, where VPAT knockout mice have been shown to be more sensitive to amphetamine and less sensitive to diazepam, suggesting a role for Spd/Spm co-transmission (Fredriksson et al., 2019)