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Chemoinformatic analysis of biologically active macrocycles

As of now, most remain restricted, unapproved, or subject to regulatory risk when compounded for human use

It's important to note that GLPs are still prescription medications and should always be used thoughtfully, with individualized medical guidance

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The legal path for compounded tirzepatide narrowed to a sliver, available only for patients with verifiable clinical needs that the commercially available formulation could not meet