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Noteworthy, SGLT2-i have been shown to interfere with sodium-hydrogen exchanger (NHE-3), which is primarily responsible for sodium tubular reuptake following filtration and is markedly increased in heart failure (HF) (42)

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Ozempic and Wegovy are FDA-approved finished drug products manufactured by Novo Nordisk under current Good Manufacturing Practice standards, reviewed by the FDA for safety, effectiveness, and quality before reaching patients

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It is also helpful for patients who are increasing doses, restarting therapy, switching medications, or trying to maintain results after significant weight loss