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29 This approach was utilized in this study to evaluate whether BDNF knockdown in specific hippocampal subregions can actually affect behaviors associated with depression and whether such a localized reduction in the BDNF protein can affect neurogenesis in vivo

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Research indicates that this peptide modulates angiogenesis through upregulation of vascular endothelial growth factor (VEGF) expression and enhancement of endothelial cell proliferation and migration