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While 14 C-labeling of peptides was previously typically limited to the use of 14 C-amino acids during multi-step SPPS or to late-stage derivatization with 14 C-tags, our platform offers late-stage generation of 14 C-labeled lysine residues

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Brain Res 680: 157163

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Moreover, using mutant GLP-1Rs, Ge et al (26) described that even with a mutation of the putative signal sequence, ligand binding to the mutant receptor was observed with conserved cAMP production