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Start Your Evaluation Safety Comparison: Side Effects and Contraindications Both medications have significant side effect profiles, but the nature of those side effects differs dramatically: Semaglutide side effects are primarily gastrointestinal: nausea (44%), diarrhea (30%), constipation (24%), and vomiting (24%)

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doi: 10.3389/fonc.2025.1548570 Received 19 December 2024 Accepted 16 April 2025 Published 05 June 2025 Volume 15 - 2025 Edited by Liang Qiao, The University of Sydney, Australia Reviewed by Satvinder Singh Mudan, The London Clinic, United Kingdom Nittaya Chamadol, Khon Kaen University, Thailand Updates Copyright 2025 Jiang, Huang and Jiang