The researchers found that turning off GLP-1 in the brain didnt affect the normal daily intake of food, but instead was important in several specific situations: prolonged fasting, large feedings, and stress-induced appetite loss.[ref] Controlling binging, regulating satiety: Essentially, the neurons activated by GLP-1 help to limit binging after a fast they keep you from massively overeating after not eating for a while
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Operation of the pathway in vivo: unresolved issues The ascorbateglutathione pathway as understood today does not easily lend itself to the use of nuclear isotopes to estimate metabolic flux between the different reactions
Srikakulapu P, McNamara CA
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