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Each member of the treatment groups received an icv injection of scopolamine hydrobromide (70 nmol in 2 aCSF over a duration of 20 s) 20 min prior to testing followed by Nle'-AnglV or one of the analogs (in 2 aCSF) 5 min prior to testing

It promotes satiation, resulting in a diminished appetite

A focused neurologic exam

Aydin 1 , Frank Te Nijenhuis 2 , Marta Rubiera 3 , Susanne Bonekamp 4 , Ronen R Leker 5 , Satoru Tanioka 1 , Theo van Walsum 2 , Charles Majoie 6 , Wim Van Zwam 7 , Sam Payabvash 8 , Thomas Tourdias 9 , Christian Nolte 10 , Dietmar Frey 1,11 1 CLAIM - Charit Lab for Artificial Intelligence in Medicine, Charit Universittsmedizin Berlin, Germany, Berlin, Germany, 2 Biomedical Imaging Group Rotterdam, Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 3 Department of Neurology, Vall dHebrn University Hospital, Barcelona, Spain, 4 Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany, 5 Stroke Unit, Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel, 6 Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands, 7 Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, Netherlands, 8 Department of Radiology, Columbia University, New York, United States, 9 Department of Neuroradiology, CHU Pellegrin, Bordeaux, France, 10 ent of Neurology with Experimental Neurology and Center for Stroke Research Berlin (CSB), Charit Universittsmedizin Berlin, Berlin, Germany, 11 Department of Neurosurgery, Charit Universittsmedizin Berlin, Berlin, Germany Background and Aims: Modelling of prognosis has the potential to improve treatment decisions and establish precision medicine in ischemic stroke