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Calcipotriol worked faster in the first four to eight weeks, but by week 12 the two treatments produced similar reductions in PASI and the B12 cream was better tolerated (Stucker 2001)

To date, studies have reported minimal adverse effects at typical research-level dosages

Surgical procedures create controlled tissue injury requiring comprehensive healing involving multiple tissue typesskin, fascia, muscle, and potentially bone, tendon, or ligament depending on the procedure

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Dihexa-mediated protection is attenuated by co-treatment with the HGF antagonist 6-AH, further evidence that HGF activation is a component of the observed protection